American Board of Family Medicine (ABFM) Practice Exam 2025 - Free ABFM Practice Questions and Study Guide

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What is the preferred medication for treating acute gout in a patient with chronic kidney disease?

Nsaids

Colchicine

Prednisone

The preferred medication for treating acute gout in a patient with chronic kidney disease is prednisone. Corticosteroids like prednisone are effective in managing acute gout attacks, particularly when NSAIDs and colchicine are not suitable due to the patient's renal status.

In chronic kidney disease, NSAIDs can increase the risk of renal function deterioration, as they can lead to further reductions in renal perfusion and exacerbate existing kidney dysfunction. Colchicine, while effective, can also pose a risk of toxicity in patients with impaired renal function, as its clearance is decreased, potentially leading to accumulation and adverse effects.

Prednisone, on the other hand, is not dependent on renal function for its effectiveness and can be safely used in patients with chronic kidney disease, making it a preferable choice for treating acute flare-ups of gout in this population. It works by reducing inflammation, thereby alleviating pain and swelling associated with gout attacks.

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Allopurinol

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